Chinese medicine in 19th century Japan culminated in the career of Mori Tachiyuki（森立之）, who came from a long line of physicians. He followed such famous scholars as Izawa Rangen（伊澤蘭軒） , and Taki Motokata（多紀元堅） to learn philology, phonology, textual research and medicine. When he was young he was banished to Sagami（相模） for 12 years, where he identified himself with farmers, hunters and local folk physicians, accumulated plenty of rich experiences and made on-the-spot observations and studies of medicinal plants, animals and minerals. After returning to Tokyo, he was long engaged in the studies of Han Learning and medical literature, and teaching. He compiled such books as “Notes to Treatise on Febrile Diseases”（傷寒論攷注） , “Notes to Synopsis of Prescriptions of the Golden Chamber”（金匱要略攷注） , “Notes to Shen Nong’s Herbal”（本草經攷注） , “Notes to PIain Questions”（素問攷注）and “A series of Notes to Zhi Yuan”（枳園叢攷）. He widely applied the ideas and methods of Chinese physicians of past dynasties and the evidential studies scholars of the Qing Dynasty, while inheriting the research achievements made by outstanding Japanese specialists in medicine, and corrected literal mistakes and misunderstandings which had spread for a long time. He also completed the Japanization of traditional Chinese medicine.